Club Drugs

Club Drugs

-Dr. Jeff Daiter

This was a lecture at the Canadian Society of Addiction Medicine Annual Meeting at the Hyatt Regency in Vancouver, BC Canada, Sept 26, 2013.  It was one of the most helpful presentations to me by a very impressive clinician and researcher.  All of us in front line addiction work encounter a deluge of names for street drugs and these recent new psychoactive drugs are the most trying. I'd heard more about them at a conference in Milan where the International Society of Addiction Medicine had a meeting and these drugs for a major concern for regulators. The danger to children was a major concern. I am sorry for my rough notes which only give a just of the excellent presentation by Dr Jeff Daiter who had superb slides which I wasn't able to copy due to time.  I hope this is helpful nonetheless.

Old def’n ‘designer drugs - 1980’s mdma

New term ‘Club Drugs”

• included GHB,

Now called RESEARCH CHEMICALS

• late 1990’s marketeers of psychedelics becuase they could import ‘research’ materials from china

Now LEGAL HIGh

-uses unscheduled to imply legal for improved credibility

NEW PSYCHACTIVE SUBSTANCES  (NPS) - best term

-psychoactive illicit drugs

• ecstacy, methamphetamine, GHB, flunitrazepin

Phenethylamines

-Dr. Alexander Shulgin - original psychonaut - first venture - he did mescaline

• introduced MDMA to Psychologists in late 70’s - unlock the Human Mind through Psychedelics.
• psychostimulants
• 4-mma and methyl-Ma;2,5 - dimethoxy-d-iodophenethylamine 2C1

he calls himself a ‘toolmaker’

in low doses increases alertness and endurance

-in higher doseses, they induce euphoria, stronger feelings of self -esteem, increased blood pressure, raised body temp, increase heart rate, cause hallucinations

• we don’t see MDMA so much but the 200 other drugs of this class that are not illegal, not yet
• Chronic use can entail psychosis

Piperazine's

-first in 1953, big in new zealand

• used first for anthelmintic properties
• most common BZP, TFMPP and mCPP
• euphoric and stimulant properties comparable to amphetamines

Ketamine

• true dissociative
• veterinarian use
• k, special k, kit kat, cat valium, vitamin k, super k, 
• originally developed as derivative of phencyclidine (PCP) drug controlled under Schedule II of the 1971 convention
• -used primary for induction and maintenance of anesthesia in animals
• K-Hole video
• people taking K are trying to get to the K Hole -lots in down town toronto

Tryptamines

 5-MeO-DMT

alpha O, foxy methoxy, AMT

-effects similar to to magic mushrooms 

Plant based NPS

-KAT

-Salvia

-Kratom  - investigated for opium dependence - stimulant at low dose and sedative at high - withdrawal may inculde muscle aches, irritability, crying, runny nose, diarrhoea, muscle jerking

Synthetic Cathinoes

• most problematic group of NPS from perspective of pblic safety and health
• stimulations simiar to amphetamines 
• have all kind of adulterants
• guy in ontario was eating live dog

Bath Salts is most unscheduled drugs getting hits on Google

Charting by Google trends

Synthetic Cathinoes have high abuse and addiction potential - but lots of unknown ingredients

Synthetic Cannabinoids

 J.W. Huffman - JWH-018  - categorized and published them and now people know how to make them - synthesized over 450 cannabinoids - organic chemist

Spice and K2 big names 2 years ago

Now called all sorts of different things - chill out

You can order off the internet

“It’s a legal high”.

Hard to engage someone in treatment - they say they’re not chasing it, 

3 deaths in Colorado due to synthetic marijuana -75 people sick

Probably not the cannabinoid that kills but what is mixed in with it in the laboratory

Synthetic Cannabinoids

Synthetic Cathiones

new emergency drugs

The mix in review - phethylamines, piperazeins, ketamines, typtamines, plant based, synthetic cathinoes, synthetic cannabinoids

Qand A

testing - seeing a lot of MPTP - metabolite of Trazadone

A- laboratory can’t keep up with what’s being used

MDMA - keeps being made with combination - toxicology - drugs by themselves may not be so bad as the combination - methedrone  - deaths in ICU

Venison Jerky

My venison marinade has olive oil, molasses, honey, garlic, onion, soy sauce, tobasca, basil, oregano, salt, lots of pepper and then some and love. I whisk it up like an alchemical brew and measure portions of other stuff that I add as I get inspired. The cat flies about the kitchen on her little broom, shrilly screeching, "eye of neut, eye of neut". But I never put eye of neut in my venison marinade and she knows that.

I cut up slices of venison ensuring only the best meat in the same 1/8 to 1/4 inch strips. I put the meat in the marinade and then covering the large bowl with saran wrap place it in the vegetable space of the refrigerator.

Overnight and the whole next day this experience happened in my fridge while I first slept and then spent the day at work. In the evening I rushed home to fire up the Big Chief electric smoker on my high rise deck in West End Vancouver. I filled the chip pan with alder then laid out each morsel of meat on the rack above. I plugged in that Big Chief and smoke and aroma began to happen almost instantly. I was barbecuing venison steaks meanwhile.

Multi cultural West End Vancouver began to experience a Canadian culinary sensual extravaganza. Aboriginal people's noses went up instantly as they began to search the city for the source of the feast of the Creator. Scots, Russians, Europeans, Northern Chinese, Africans, and all the others whose fathers had hunted deer and raised their children on the succulent experience of smoked meat salivated en mass.

Meanwhile my neighbour above me not one to appreciate the aroma of alder and venison smoke pointed a garden hose down at my deck and tried to flood me out. At first I thought it was raining but when I went out to get my steaks sure enough there was the garden hose nozzle conspicuously aimed over the side of the above deck. Poor aim. The smoking process continued overnight with very little smoke but the richest aroma. I added more alder a half dozen times and the garden hose shut off after an hour or so of token resistance. Her DNA will never be the same and she has given up vegetarianism and applied for a hunting license on line.

This morning I again had a taste of heaven. Unbelievable! But again the battle began. I want to share the experience. I want to watch another human's lips smack and eyes roll back in venison jerky rapture but I don't want to share my hoard. I know it's downright sinful and I should give it all to the church to save me from pride of possession. It's all I can do to resist devouring the whole bowl.

Meanwhile I wouldn't be surprised if my neighbour approached me offering sex for venison. It wouldn't be the first time. My aboriginal friends get that all the time when they smoke up salmon. I'd refuse of course. Its a sacred not secular experience.